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The in vitro dissolution of formulations C1 to C7 (the first 2 h in an acid medium of pH 1.2, and then in a phosphate buffer medium of pH 6.8).
| Time | Percent Drug Release (%) | ||||||
|---|---|---|---|---|---|---|---|
| Hour | C1 | C2 | C3 | C4 | C5 | C6 | C7 |
| 1 | 1 | 1 | 0.2 | 0.1 | 0.01 | 0 | 0 |
| 2 | 2 | 3 | 1 | 0.5 | 0.1 | 0 | 0 |
| 3 | 10 | 7 | 1 | 0.7 | 1 | 0 | 0 |
| 4 | 11 | 10 | 5 | 2 | 1.7 | 0.2 | 0 |
| 5 | 28 | 21 | 10 | 7 | 3 | 0.9 | 0 |
| 6 | 52 | 61 | 30 | 11 | 6 | 5 | 1 |
| 7 | 69 | 78 | 56 | 21 | 10 | 7 | 2 |
