Figure 5.

Schematic representation reporting the association between the levels of sex hormones and keratinocyte functions in inflammatory skin disorders. The role of sex hormones, keratinocyte functions and cutaneous immunity in Hidradenitis suppurativa, Atopic dermatitis, progesterone hypersensitivity, psoriasis and Acne vulgaris. In the indicated processes, the arrows facing upwards (↑) indicate an upregulation, while the arrows facing downwards (↓) indicate a downregulation. Estrogen is indicated with a red dot, progesterone by an orange dot and androgens by a blue dot.