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. 2022 Feb 27;14(3):487. doi: 10.3390/v14030487

Figure 1.

Figure 1

Partial genome comparison between the 4 PEDV strains in this study and the reference strains. (a) Compared with CV777 strain, the 4 strains displayed common 3 aa deletions or 5 aa insertions occurring in the N-terminal domain of the S protein, of which a distinct change (N140Y) in the insertion site was observed in CH-HNYY-2018. (b) The ORF3 gene of classic virulent strain CV777 was complete, and the attenuated DR13 strain had 49 nucleotide deletions at 245–293 nt, CO/P14/IC possessed 37 nucleotide deletions at 240–276 nt, the naturally truncated strain HN2021 exhibited 167 continuous nucleotide deletions at 207–373 nt. (c) Attenuated-DR13, HLJBY and PEDV-SX ORF3 proteins were 91 aa, which had 133 aa deletions at C’. CO/P14/IC ORF3 protein was 80 aa, with 144 aa deletions at C’ end, and the HN2021 owned the shortest ORF3 protein of all strains in this study, which was 68 aa, with 156 aa deletions at C’ end.