The evaluation of parasitemia in mice infected with Trypanosoma congolense and orally treated with different concentrations of nitrofurantoin. The Y-axis shows log 10 scale, and 103 indicates no parasites in 100-fold diluted blood, as determined using a cell counting chamber. Significant suppression of parasitemia (p < 0.05) was observed on 6, 8, and 9 dpi in group III (10 mg/kg), and on 6 to 9 dpi in other groups in comparison with that in the control group (Group II) from days 6 to 9. The data are shown as the mean ± standard deviation values. Orange highlight: NF treatment from 4 dpi to 10 dpi.