Table 4.

Clinical Pathology Reference Intervals by Age in Female Marmosets.

Analyte	Unit	Age	Range	Median	Samples, n	Lower 95% CI	Upper 95% CI	P value compared with female adults	Effect Size
Weight	g	Juvenile/subadult	294.7-521.7	408	52	279.3 - 310.1	506.3 - 537.2
Weight	g	Adult	327.0-532.6	427	79	315.6 - 338.3	521.3 - 543.9
Weight	g	Geriatric	364.7-506.0	438	45	354.3 - 375	495.7 - 516.4
Alanine aminotransferase (ALT)	U/L	Juvenile/subadult	0.0-25.3	7.5	102	0 - 0	23.9 - 26.8
Alanine aminotransferase (ALT)	U/L	Adult	0.0-21.6	7	87	0 - 0	20.3 - 22.9
Alanine aminotransferase (ALT)	U/L	Geriatric	1.7-17.2	8.5	42	0.5 - 2.8	16.1 - 18.4
Albumin	g/dL	Juvenile/subadult	3.6-5.2	4.4	110	3.5 - 3.6	5.1 - 5.2	3.40E-03	0.4 (S)
Albumin	g/dL	Adult	3.3-5.1	4.2	100	3.2 - 3.4	5 - 5.2
Albumin	g/dL	Geriatric	2.7-4.5	3.6	49	2.5 - 2.8	4.4 - 4.7	0.00E+00	−1.3 (L)
Albumin/Globulin (A:G) ratio		Juvenile/subadult	1.5-2.8	2.2	48	1.5 - 1.6	2.7 - 2.9	1.50E-03	0.6 (M)
Albumin/Globulin (A:G) ratio		Adult	1.4-2.6	1.9	65	1.3 - 1.4	2.5 - 2.7
Albumin/Globulin (A:G) ratio		Geriatric	1.1-2.1	1.6	35	1 - 1.2	2.1 - 2.2	0.00E+00	−1.3 (L)
Alkaline Phosphatase (ALP)	U/L	Juvenile/subadult	34.7-153.8	88	93	28.6 - 40.7	147.7 - 159.9	0.00E+00	1.3 (L)
Alkaline Phosphatase (ALP)	U/L	Adult	13.1-104.9	54	102	8.7 - 17.6	100.5 - 109.4
Alkaline Phosphatase (ALP)	U/L	Geriatric	22.6-92.3	52.5	48	17.6 - 27.5	87.4 - 97.3
Amylase	U/L	Juvenile/subadult	159.6-316.4	237	55	149.2 - 169.9	306 - 326.7
Amylase	U/L	Adult	147.0-309.2	229	91	138.7 - 155.4	300.9 - 317.6
Amylase	U/L	Geriatric	132.4-331.3	218	43	117.5 - 147.2	316.4 - 346.2
Anion Gap	mM/L	Juvenile/subadult	17.8-30.5	25	20	16.4 - 19.2	29.1 - 31.9
Anion Gap	mM/L	Adult	18.4-29.6	23	30	17.4 - 19.4	28.6 - 30.6
Anion Gap	mM/L	Geriatric	19.6-30.1	24	27	18.6 - 20.6	29.1 - 31.1
Aspartate aminotransferase (AST)	U/L	Juvenile/subadult	46.4-175.5	106.5	94	39.9 - 52.9	169 - 182
Aspartate aminotransferase (AST)	U/L	Adult	45.6-177.6	107	73	38 - 53.2	170 - 185.2
Aspartate aminotransferase (AST)	U/L	Geriatric	56.1-171.5	108	41	47.3 - 65	162.7 - 180.3
Blood Urea Nitrogen (BUN)	mg/dL	Juvenile/subadult	12.8-32.7	22	106	11.8 - 13.7	31.8 - 33.7	0.00E+00	0.8 (M)
Blood Urea Nitrogen (BUN)	mg/dL	Adult	9.7-28.5	20	101	8.8 - 10.7	27.5 - 29.4
Blood Urea Nitrogen (BUN)	mg/dL	Geriatric	8.8-29.9	19	48	7.3 - 10.3	28.4 - 31.4
BUN/Creatinine (B:C) ratio		Juvenile/subadult	2.0-144.9	70	32	0 - 14.4	132.5 - 157.3
BUN/Creatinine (B:C) ratio		Adult	0.0-159.9	70	33	0 - 0	144.1 - 175.7
BUN/Creatinine (B:C) ratio		Geriatric	0.7-168.3	66.7	28	0 - 16.2	152.8 - 183.8
Calcium	mg/dL	Juvenile/subadult	9.1-11.4	10.2	108	9 - 9.2	11.3 - 11.5	2.00E-04	0.6 (M)
Calcium	mg/dL	Adult	8.5-11.2	9.9	100	8.4 - 8.7	11.1 - 11.3
Calcium	mg/dL	Geriatric	8.3-10.4	9.3	49	8.2 - 8.5	10.3 - 10.6	0.00E+00	−0.8 (M)
Chloride	mM/L	Juvenile/subadult	100.1-112.3	107	39	99.2 - 101.1	111.4 - 113.3
Chloride	mM/L	Adult	100.9-113.0	107	54	100.1 - 101.7	112.2 - 113.8
Chloride	mM/L	Geriatric	103.5-114.0	109	35	102.7 - 104.4	113.1 - 114.8	8.80E-03	0.6 (M)
Cholesterol	mg/dL	Juvenile/subadult	57.2-210.1	129.5	48	46.3 - 68	199.3 - 220.9
Cholesterol	mg/dL	Adult	32.8-224.9	118	66	21.3 - 44.4	213.3 - 236.5
Cholesterol	mg/dL	Geriatric	60.9-294.1	186	35	41.5 - 80.2	274.8 - 313.4	3.00E-04	0.9 (L)
Creatine Kinase (CK)	U/L	Juvenile/subadult	0.0-753.1	254	25	0 - 0	668.2 - 838.1
Creatine Kinase (CK)	U/L	Adult	0.0-909.6	197	37	0 - 0	814.5 - 1004.7
Creatine Kinase (CK)	U/L	Geriatric	0.0-1071.5	264	24	0 - 0	940.6 - 1202.5
Creatinine	mg/dL	Juvenile/subadult	0.1-0.4	0.3	45	0.1 - 0.1	0.4 - 0.4	3.26E-02	0.5 (M)
Creatinine	mg/dL	Adult	0.1-0.4	0.2	54	0 - 0.1	0.3 - 0.4
Creatinine	mg/dL	Geriatric	0.0-0.4	0.2	32	0 - 0.1	0.4 - 0.5
Direct Bilirubin	mg/dL	Juvenile/subadult	0.0-0.0	0	31	0 - 0	0 - 0
Direct Bilirubin	mg/dL	Adult	0.0-0.0	0	33	0 - 0	0 - 0
Direct Bilirubin	mg/dL	Geriatric	0.0-0.0	0	30	0 - 0	0 - 0
Gammaglutamyl transferase (GGT)	U/L	Juvenile/subadult	0.0-14.8	6	55	0 - 0	13.7 - 15.9
Gammaglutamyl transferase (GGT)	U/L	Adult	0.0-13.5	4	77	0 - 0	12.6 - 14.4
Gammaglutamyl transferase (GGT)	U/L	Geriatric	1.5-14.3	7	43	0.6 - 2.5	13.3 - 15.2	6.00E-04	0.6 (M)
Globulin	g/dL	Juvenile/subadult	1.6-2.6	2.1	111	1.5 - 1.6	2.6 - 2.7
Globulin	g/dL	Adult	1.6-2.7	2.1	98	1.5 - 1.6	2.7 - 2.8
Globulin	g/dL	Geriatric	1.7-2.7	2.1	48	1.7 - 1.8	2.6 - 2.8
Glucose	mg/dL	Juvenile/subadult	31.3-229.9	120	105	21.8 - 40.8	220.4 - 239.4
Glucose	mg/dL	Adult	23.5-248.7	125	96	12.2 - 34.8	237.4 - 259.9
Glucose	mg/dL	Geriatric	24.9-199.6	107	49	12.7 - 37.1	187.3 - 211.8
Indirect Bilirubin	mg/dL	Juvenile/subadult	0.0-0.2	0.1	34	0 - 0	0.2 - 0.2
Indirect Bilirubin	mg/dL	Adult	0.0-0.2	0.1	40	0 - 0	0.2 - 0.2
Indirect Bilirubin	mg/dL	Geriatric	0.0-0.2	0.1	30	0 - 0	0.2 - 0.2
Lipase	IU/L	Juvenile/subadult	11.6-46.7	28	37	8.8 - 14.4	43.9 - 49.6
Lipase	IU/L	Adult	9.4-45.9	26	65	7.2 - 11.7	43.7 - 48.1
Lipase	IU/L	Geriatric	13.7-46.4	28	37	11.1 - 16.4	43.8 - 49.1
Phosphorus	mg/dL	Juvenile/subadult	2.5-5.6	4.1	61	2.3 - 2.7	5.4 - 5.8	9.00E-04	0.5 (M)
Phosphorus	mg/dL	Adult	1.9-5.4	3.6	94	1.7 - 2.1	5.2 - 5.5
Phosphorus	mg/dL	Geriatric	2.1-5.5	3.6	46	1.8 - 2.3	5.2 - 5.7
Potassium	mM/L	Juvenile/subadult	2.2-3.9	3	38	2.1 - 2.4	3.8 - 4.1
Potassium	mM/L	Adult	2.4-3.9	3.2	53	2.3 - 2.5	3.8 - 4
Potassium	mM/L	Geriatric	2.3-3.9	3.1	36	2.2 - 2.5	3.8 - 4
Sodium	mM/L	Juvenile/subadult	145.9-154.0	150	39	145.3 - 146.5	153.3 - 154.6
Sodium	mM/L	Adult	145.8-154.3	150	54	145.2 - 146.3	153.8 - 154.9
Sodium	mM/L	Geriatric	146.0-155.2	151	36	145.2 - 146.7	154.5 - 156
Sodium/Potassium (Na:K) ratio		Juvenile/subadult	34.7-62.4	50	27	32 - 37.3	59.8 - 65
Sodium/Potassium (Na:K) ratio		Adult	33.4-57.5	46	31	31.3 - 35.5	55.4 - 59.6
Sodium/Potassium (Na:K) ratio		Geriatric	36.8-61.6	49	28	34.5 - 39.1	59.3 - 63.9
Total Bilirubin	mg/dL	Juvenile/subadult	0.0-0.2	0.1	64	0 - 0	0.2 - 0.2
Total Bilirubin	mg/dL	Adult	0.0-0.2	0.1	95	0 - 0	0.2 - 0.2
Total Bilirubin	mg/dL	Geriatric	0.0-0.2	0.1	46	0 - 0	0.2 - 0.2	1.05E-02	−0.5 (M)
Total CO2 (Bicarbonate)	mM/L	Juvenile/subadult	16.1-28.3	22	26	14.9 - 17.2	27.1 - 29.5
Total CO2 (Bicarbonate)	mM/L	Adult	15.9-27.9	22	36	14.9 - 16.9	26.9 - 28.9
Total CO2 (Bicarbonate)	mM/L	Geriatric	12.7-27.1	20	29	11.4 - 14	25.8 - 28.4	3.39E-02	−0.6 (M)
Total Protein	g/dL	Juvenile/subadult	5.3-7.6	6.5	111	5.2 - 5.4	7.5 - 7.7
Total Protein	g/dL	Adult	5.1-7.5	6.4	100	5 - 5.3	7.4 - 7.6
Total Protein	g/dL	Geriatric	4.8-6.9	5.9	50	4.6 - 4.9	6.7 - 7	0.00E+00	−0.9 (L)
Bands	$\times {10}^3$/µL	Juvenile/subadult	0.0-5.7	1	6	0 - 0	4.2 - 7.3
Bands	$\times {10}^3$/µL	Adult	0.0-4.5	1	8	0 - 0	3.5 - 5.5
Bands	$\times {10}^3$/µL	Geriatric	0.0-3.7	1	8	0 - 0	3 - 4.5
Basophil #	$\times {10}^3$/µL	Juvenile/subadult	0.0-0.0	0	26	0 - 0	0 - 0
Basophil #	$\times {10}^3$/µL	Adult	0.0-0.0	0	32	0 - 0	0 - 0
Basophil #	$\times {10}^3$/µL	Geriatric	0.0-0.0	0	23	0 - 0	0 - 0
Basophil %	%	Juvenile/subadult	0.0-0.6	0.1	27	0 - 0	0.5 - 0.6
Basophil %	%	Adult	0.0-0.6	0.1	29	0 - 0	0.5 - 0.7
Basophil %	%	Geriatric	0.0-0.5	0.2	23	0 - 0	0.4 - 0.5
Eosinophil #	$\times {10}^3$/µL	Juvenile/subadult	0.0-0.2	0.1	26	0 - 0	0.2 - 0.2
Eosinophil #	$\times {10}^3$/µL	Adult	0.0-0.3	0.1	40	0 - 0	0.3 - 0.3
Eosinophil #	$\times {10}^3$/µL	Geriatric	0.0-0.2	0.1	24	0 - 0	0.2 - 0.3
Eosinophil %	%	Juvenile/subadult	0.3-3.6	1.7	26	0 - 0.6	3.3 - 3.9
Eosinophil %	%	Adult	0.4-3.8	1.95	38	0.1 - 0.6	3.5 - 4
Eosinophil %	%	Geriatric	0.0-3.7	1.5	24	0 - 0.2	3.3 - 4
Hematocrit (HCT)	%	Juvenile/subadult	32.4-45.1	39.45	38	31.3 - 33.4	44.1 - 46.2
Hematocrit (HCT)	%	Adult	31.3-44.0	37.5	53	30.4 - 32.1	43.2 - 44.9
Hematocrit (HCT)	%	Geriatric	29.6-47.8	38.65	32	28 - 31.2	46.2 - 49.4
Hemoglobin (Hgb)	g/dL	Juvenile/subadult	11.7-15.9	13.8	39	11.4 - 12.1	15.6 - 16.2
Hemoglobin (Hgb)	g/dL	Adult	10.9-15.8	13.2	51	10.6 - 11.2	15.5 - 16.1
Hemoglobin (Hgb)	g/dL	Geriatric	10.3-16.6	13.2	34	9.8 - 10.8	16 - 17.1
Lymphocyte #	$\times {10}^3$/µL	Juvenile/subadult	0.3-5.3	2.6	27	0 - 0.7	4.8 - 5.8
Lymphocyte #	$\times {10}^3$/µL	Adult	0.0-4.9	2.2	37	0 - 0.4	4.5 - 5.3
Lymphocyte #	$\times {10}^3$/µL	Geriatric	0.0-5.5	2.05	24	0 - 0.3	4.9 - 6.1
Lymphocyte %	%	Juvenile/subadult	19.9-91.8	57	28	13.3 - 26.6	85.2 - 98.5
Lymphocyte %	%	Adult	14.4-81.8	45.95	40	9.2 - 19.6	76.6 - 87.1
Lymphocyte %	%	Geriatric	6.7-73.5	31.75	24	0 - 13.3	66.8 - 80.1
Mean corpuscular hemoglobin (MCH)	pg	Juvenile/subadult	16.1-23.0	19.35	38	15.6 - 16.7	22.5 - 23.6
Mean corpuscular hemoglobin (MCH)	pg	Adult	16.8-23.0	19.9	53	16.4 - 17.2	22.5 - 23.4
Mean corpuscular hemoglobin (MCH)	pg	Geriatric	17.8-23.2	20.75	36	17.3 - 18.2	22.8 - 23.7
Mean corpuscular hemoglobin concentration (MCHC)	g/dL	Juvenile/subadult	31.0-39.5	35.05	38	30.4 - 31.7	38.8 - 40.1
Mean corpuscular hemoglobin concentration (MCHC)	g/dL	Adult	31.5-39.5	35.7	54	31 - 32	39 - 40
Mean corpuscular hemoglobin concentration (MCHC)	g/dL	Geriatric	29.2-39.7	34.55	36	28.3 - 30.1	38.8 - 40.6
Mean corpuscular volume (MCV)	fL	Juvenile/subadult	49.5-61.9	55.5	39	48.5 - 50.5	61 - 62.9
Mean corpuscular volume (MCV)	fL	Adult	50.1-62.2	55.5	51	49.2 - 50.9	61.4 - 63.1
Mean corpuscular volume (MCV)	fL	Geriatric	51.5-66.2	58.5	34	50.3 - 52.8	64.9 - 67.4	2.60E-03	0.8 (L)
Mean platelet volume (MPV)	fL	Juvenile/subadult	7.4-12.3	9.8	38	7 - 7.8	11.9 - 12.7
Mean platelet volume (MPV)	fL	Adult	7.2-13.2	10.05	56	6.8 - 7.6	12.8 - 13.5
Mean platelet volume (MPV)	fL	Geriatric	6.2-12.9	9.5	37	5.7 - 6.7	12.4 - 13.5
Monocyte #	$\times {10}^3$/µL	Juvenile/subadult	0.0-0.3	0.1	26	0 - 0	0.2 - 0.3
Monocyte #	$\times {10}^3$/µL	Adult	0.0-0.3	0.2	37	0 - 0	0.3 - 0.3
Monocyte #	$\times {10}^3$/µL	Geriatric	0.0-0.3	0.1	24	0 - 0	0.2 - 0.3
Monocyte %	%	Juvenile/subadult	0.2-4.8	2.25	26	0 - 0.7	4.4 - 5.3
Monocyte %	%	Adult	0.1-6.0	2.7	39	0 - 0.5	5.6 - 6.5
Monocyte %	%	Geriatric	0.0-4.6	1.9	24	0 - 0.2	4.1 - 5.1
Neutrophil #	$\times {10}^3$/µL	Juvenile/subadult	0.0-4.7	1.75	28	0 - 0	4.2 - 5.1
Neutrophil #	$\times {10}^3$/µL	Adult	0.0-5.3	1.9	37	0 - 0	4.9 - 5.8
Neutrophil #	$\times {10}^3$/µL	Geriatric	0.7-6.3	3.1	23	0.1 - 1.2	5.7 - 6.9	4.40E-03	0.8 (M)
Neutrophil %	%	Juvenile/subadult	6.3-66.6	35.65	28	0.7 - 11.9	61 - 72.2
Neutrophil %	%	Adult	14.4-75.5	47.4	40	9.7 - 19.2	70.8 - 80.2
Neutrophil %	%	Geriatric	23.7-87.9	60.65	24	17.3 - 30.1	81.5 - 94.4	2.22E-02	0.7 (M)
Platelet count (PLT)	$\times {10}^3$/µL	Juvenile/subadult	39.0-53.2	45.5	68	38.1 - 39.8	52.4 - 54.1
Platelet count (PLT)	$\times {10}^3$/µL	Adult	38.6-52.8	45	54	37.6 - 39.5	51.9 - 53.8
Platelet count (PLT)	$\times {10}^3$/µL	Geriatric	36.9-49.0	43	15	35.4 - 38.4	47.4 - 50.5	2.75E-02	−0.8 (M)
Red blood cell count (RBC)	$\times {10}^6$/µL	Juvenile/subadult	157.5-587.3	359	38	123.3 - 191.7	553.2 - 621.5
Red blood cell count (RBC)	$\times {10}^6$/µL	Adult	130.7-711.9	404.5	54	91.9 - 169.4	673.2 - 750.7
Red blood cell count (RBC)	$\times {10}^6$/µL	Geriatric	236.7-876.3	595.5	34	182.9 - 290.4	822.6 - 930.1	8.00E-04	0.9 (L)
Red cell distribution width (RDW)	%	Juvenile/subadult	5.9-8.3	7.005	38	5.7 - 6	8.1 - 8.5	4.53E-02	0.6 (M)
Red cell distribution width (RDW)	%	Adult	5.3-8.1	6.72	51	5.1 - 5.5	7.9 - 8.3
Red cell distribution width (RDW)	%	Geriatric	5.1-8.2	6.725	34	4.9 - 5.4	7.9 - 8.4
Packed Cell Volume (PCV)	%	Juvenile/subadult	14.2-20.2	16.7	37	13.7 - 14.6	19.7 - 20.6
Packed Cell Volume (PCV)	%	Adult	14.8-19.0	16.65	52	14.5 - 15.1	18.7 - 19.3
Packed Cell Volume (PCV)	%	Geriatric	14.4-18.3	16.15	36	14.1 - 14.7	17.9 - 18.6	3.96E-02	−0.5 (M)
White blood cell count (WBC)	$\times {10}^3$/µL	Juvenile/subadult	1.7-8.2	4.8	38	1.2 - 2.2	7.7 - 8.7
White blood cell count (WBC)	$\times {10}^3$/µL	Adult	0.8-8.4	4.15	48	0.3 - 1.4	7.8 - 8.9
White blood cell count (WBC)	$\times {10}^3$/µL	Geriatric	2.7-9.0	5.8	35	2.2 - 3.3	8.5 - 9.5	7.70E-03	0.7 (M)

N = negligible, S = small, M = medium, L = large