Fig. 1. The crystal structure of OdinTubulin.
(A) Phylogenetic analysis of OdinTubulin from structure-based sequence alignment in comparison to the prokaryotic cell division proteins, FtsZ and CetZ, and the eukaryotic microtubule-forming tubulins. (B) Comparison of the protomer structures of GTP-bound OdinTubulin (PDB 7EVB) to β-tubulin (PDB 6o2r) (19), CetZ (PDB 4b45) (2), and FtsZ (PDB 1w5a) (4). The matching numbers of residues and RMSD values indicate the relative structural similarities to OdinTubulin. RMSD, root mean square deviation. (C) Superimposition of the two GTP-bound OdinTubulin symmetry-related subunits from the crystal packing (dark blue) onto two subunits of eukaryotic tubulin from the GDP-bound microtubule (PDB 6o2r) (19).