Table 1. Quantitative analysis of calcium release units (CRUs).

In soleus fibers from TMP269 + 5-aza-2-deoxycytidine (5-Aza)-treated double heterozygous (dHT) mice, frequency of total CRUs and dyads (incomplete CRUs) are significantly rescued (columns A and B), suggesting a better preservation of CRUs and improved structure of triads.

	A	B	C
	No. of CRUs/100 µm2	% of dyads	% of oblique longitudinal CRUs
Soleus Vehicle treated	40.3 ± 2.4	14.2 ± 3.6	10.7 ± 2.0
Soleus TMP269 + 5-Aza treated	*46.9 ± 2.3	†6.5 ± 0.6	10.6 ± 2.6

Data are shown as mean ± SEM; n = 2 vehicle-treated soleus muscles; n=3 drug-treated soleus muscle.

^*p = 0.0248.

^†p = 0.0001.