Table 2. Quantitative analysis of mitochondria.

Soleus fibers from TMP269 + 5-aza-2-deoxycytidine (5-Aza)-treated double heterozygous (dHT) mice show a significant improvement in frequency, disposition, and morphology of mitochondria.

	A	B	C
	No. of mitochondria in 100 µm2	No. of severely altered mitochondria in 100 µm2 (%)	No. of mitochondrion/CRU pairs in 100 µm2
Soleus Vehicle treated	59.7 ± 2.9	3.2 ± 0.5 (6.2)	26.9 ± 2.2
Soleus Drug treated	*71.0 ± 3.5	†2.9 ± 0.6 (3.7)	‡34.5 ± 2.3

Data are shown as mean ± SEM; n = 2 vehicle-treated soleus muscles; n=3 drug-treated soleus muscles.

^*p = 0.0175.

^†p = 0.0475.

^‡p=0.0201.