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. 2022 Mar 23;14(1):2056291. doi: 10.1080/20002297.2022.2056291

Figure 1.

Figure 1.

Inhibitory effect of NAM on S. mutans in the planktonic state. The effect of NAM on the growth of S. mutans UA159 (a) and clinical strains (b). The effect of NAM on the glycolytic pH drop (c) and lactate dehydrogenase (LDH) activity (d and e) of S. mutans cells and biofilm. (f)The effect of NAM on the survival rate of S. mutans at pH = 5.0. N0 and N represent CFU counts before and after 2 h treatment at pH = 5.0 culture, respectively. Values represent the means and standard deviations from three independent experiments (*P < 0.05, and ***P < 0.001 compared with the untreated control).