Table 2.

Clinical characteristics of the total sample and comparison between clinical characteristics of patients pre- and during COVID-19 period:

Variables	Total sample N = 5313	Pre COVID-19 N = 2795	During COVID-19 N = 2518	p-value
Age (years)*	66.7 (14)	68 (58–77)	67 (57–76)	< 0.01
Male gender, %	55.6%	55.2%	56.1%	0.54
Management, %				0.054
Standard	78.8%	79.4% (2219)	78% (1965)
rtPA	15.9%	16.1% (450)	15.8% (397)
Thrombectomy	2.8%	2.3% (65)	3.3% (84)
rtPA and thrombectomy	2.5%	2.2% (61)	2.9% (72)
Onset to door (minutes)*	360 (162–1022)	370 (154–1199)	360 (165–901)	0.161
Door to needle (minutes)*	41 (30–57)	38 (30–49)	45 (30–64)	< 0.01
Door to groin (minutes)*	121 (80–177)	122 (72–180)	121 (91–175)	0.616
Hospitalization (days)*	7 (4–11)	7 (4–12)	7 (3–10)	< 0.01
NIHSS baseline*	9 (4–15)	8 (4–14)	10 (3–16)	< 0.01
NIHSS 24 h*	7 (3–12)	6 (3–10)	8 (4–12)	< 0.01
NIHSS discharge*	6 (2–11)	5 (2–11)	6 (2–11)	0.280
mRS discharge	33%	34.9%	31.1%	0.005
mRS 3 months	40.2%	42.5%	37.4%	< 0.01

mRS, favorable outcome < 2, *median (interquartile range); p value, between clinical characteristics of patients over the two time periods