Table 4.
Adjusted odds ratio of associating factors for predicting osteoporosis and osteopenia in female patients.
| Model | Model 1 Odds ratio (95% CI) P value |
Model 2 Odds ratio (95% CI) P value |
Model 3 Odds ratio (95% CI) P value |
||
|---|---|---|---|---|---|
| Total (n = 182) | MACS (n = 99) | Total cases (n = 182) | MACS (n = 99) | Total (n = 182) | |
| Cortisol excessa | 2.561 (1.142–5.742) 0.022∗ |
1.686 (0.687–4.140) 0.254 |
1.124 (1.063–1.189) <0.001∗ |
1.129 (1.005–1.267) 0.041∗ |
3.833 (1.829–8.030) <0.001∗ |
| Age, years. | 1.010 (0.987–1.035) 0.386 |
1.041 (1.002–1.083) 0.041∗ |
1.031 (1.004–1.059) 0.027∗ |
1.047 (1.006–1.090) 0.024∗ |
1.025 (0.998–1.052) 0.067 |
| BMI, kg/m2 | 0.947 (0.886–1.012) 0.109 |
0.972 (0.894–1.057) 0.508 |
0.941 (0.877–1.009) 0.086 |
0.963 (0.884–1.049) 0.390 |
0.931 (0.867–1.000) 0.051 |
aCortisol excess was evaluated by positivity of 1 mg DST cortisol level >5.0 µg/dL (vs. 1 mg DST cortisol level of 1.9–5.0 μg/dL) in model 1, continuous valuables of 1 mg DST cortisol (µg/dL) in model 2, and the presence of cushingoid features in model 3. Values were adjusted by age and BMI. ∗All P values <0.05 were considered statistically significant. BMI, body mass index; CI, confidential interval; DST, overnight dexamethasone suppression test; MACS, mild autonomous cortisol secretion.