Table 4.

Multivariable logistic regression for late grade ≥ 2 toxicity

Variable	OR (95% CI)	P value
Genitourinary toxicity
Age at treatment (1-y increase)	1.02 (0.98–1.06)	.343
Dose/fraction (ref = 8 Gy)
7 vs 8 Gy	0.18 (0.06–0.54)	.002
7.25 vs 8 Gy	0.25 (0.11–0.56)	.001
ADT use (yes vs no)	4.34 (1.68–11.2)	.002
Nodal radiation therapy (yes vs no)	1.53 (0.75–3.13)	.243
Gastrointestinal toxicity
Age at treatment (1-y increase)	0.98 (0.93–1.03)	.475
Dose/fraction (ref = 8 Gy)
7 vs 8 Gy	0.1 (0.02–0.54)	.008
7.25 vs 8 Gy	0.2 (0.07–0.57)	.002
ADT use (yes vs no)	0.11 (0.02–0.58)	.009
Nodal radiation therapy (yes vs no)	0.66 (0.28–1.59)	.358

Abbreviations: ADT = androgen deprivation therapy; CI = confidence interval; OR = odds ratio.