Table 1.
Characteristics of patients’ samples.
| Variables | Engraftment | Failure | P-valuea | |
|---|---|---|---|---|
| Number (%) | 105 (66%) | 55 (34%) | ||
| Patient age, median (range) | 65 (18–92) | 64 (24–86) | 0.621 | |
| Disease | de novo AML | 84 | 41 | 0.373 |
| FAB classification | ||||
| M0 | 2 | 1 | 0.028 | |
| M1 | 15 | 5 | ||
| M2 | 14 | 17 | ||
| M3 | 8 | 5 | ||
| M4 | 38 | 9 | ||
| M5 | 6 | 3 | ||
| M6 | 1 | 0 | ||
| M7 | 0 | 1 | ||
| AML with MRC | 12 | 12 | ||
| tAML from MPN | 6 | 2 | ||
| AL of ambiguous lineage | 2 | 0 | ||
| CML-BC | 1 | 0 | ||
| Cytogenetic risk | Favorable | 10 | 14 | 0.053 |
| Intermediate | 48 | 25 | ||
| Poor | 37 | 16 | ||
| Not examined | 10 | 0 | ||
| ELN risk categoryb | Favorable | 10 | 11 | 0.022 |
| Intermediate | 21 | 17 | ||
| Adverse | 59 | 20 | ||
| unknown | 7 | 2 | ||
| Graft source | BM/PB | 69/36 | 44/11 | 0.060 |
| Sample | New/relapse/refractory | 58/29/18 | 48/5/2 | <0.001 |
| Infused cell count | ≥ 5 × 106 | 95 | 39 | 0.001 |
| < 5 × 106 | 10 | 16 | ||
| Infused blast %, median (range) | 58.4 (1–100) | 46.3 (3–99.5) | 0.280 | |
| Engraft day, median (range) | 106 (27–380) | - | - | |
aChi-square test for Graft source, Fisher’s exact test for other categorical data and the Mann–Whitney U-test for continuous variables.
bAPL excluded.