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. 2021 Apr 19;36(4):766–772. doi: 10.1038/s41433-021-01538-6

Table 2.

Clinical signs of AI patients, classified according to asymptomatic or symptomatic dry eye group.

Clinical signs Total Asymptomatic Symptomatic p
Total no. of eyes 50 18 32
Visual acuity (logMAR)a 0.03 ± 0.1 0.03 ± 0.1 0.03 ± 0.1 0.992
NIBUT—1st (secs)a 7.9 ± 5.6 6.1 ± 4.3 8.8 ± 6.0 0.063
NIBUT—Average (secs)a 11.0 ± 6.1 8.6 ± 5.5 12.4 ± 6.1 0.034
Tear meniscus (mm) 0.26 ± 0.1 0.24 ± 0.1 0.27 ± 0.1 0.405
Conjunctival Inflammation 1.5 ± 0.4 1.4 ± 0.4 1.5 ± 0.5 0.398
Tear osmolarity (mOsm/L) 317 ± 21 307 ± 10 323 ± 23 0.002
Corneal staininga 0 (0–1) 0 (0–1) 0 (0–1) 0.296
Schirmer score (mm) 16.0 ± 11.7 14.4 ± 12.3 16.8 ± 11.4 0.490
Meibography—Upper lida 1 (0–1) 0 (0–1) 2 (1–2) 0.012
Meibography—Lower lida 2 (1–3) 2 (1–3) 2 (1–3) 0.236
Meibography total scorea 3 (2–4) 1 (1–3) 4 (2–4) 0.002

Key: NIBUT Non-invasive tear break up time, secs seconds, mm millimeter, mOsm/L Milliosmoles per litre.

aMann–Whitney U test.

Bold values shown significant difference i.e. p < 0.05.