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. 2022 Mar 25;12:5160. doi: 10.1038/s41598-022-09163-3

Table 3.

Selected differential expressed P. pinaster miRNAs and predicted target genes.

miRNA Expression pattern Log2FC Target ID Target annotation GO terms/pathways
DE miRNAs inoculated vs control
ppi-miR166f Downregulated  − 0.623 unigene8322 Protein TIFY 6B-like Plant hormone signal transduction
unigene942 Protein TIFY 6B Plant hormone signal transduction
ppi-miR947e Downregulated  − 1.214 unigene105220 Protein TIFY 10A Plant hormone signal transduction
ppi-miRnovel43f Downregulated  − 1.541 unigene26097 Transcription factor MYC4-like Plant hormone signal transduction
ppi-miR390b Downregulated  − 2.065 unigene3146 Nematode resistance protein-like HSPRO1 Defence response
ppi-miR11565a-i Upregulated 3.734 (± 1.83) isotig42180 WRKY transcription factor 20 Plant–pathogen interaction
unigene650 WRKY transcription factor 44 Plant–pathogen interaction
ppi-miRnovel816 Upregulated 1.754 isotig42166 Calcium-dependent protein kinase 28 (CPK28) Plant–pathogen interaction
ppi-miR11565h Upregulated 5.948 unigene12702 Disease resistance RPP13-like protein 4 Plant–pathogen interaction
ppi-miR11458e Upregulated 6.313 isotig49219 Disease resistance protein At1g61300 Plant–pathogen interaction
ppi-miR11458f Upregulated 5.155 unigene57660 Disease resistance protein RPS2 Plant–pathogen interaction
ppi-miR3627u Upregulated 5.053 isotig51344 Disease resistance protein RPS2-like Plant–pathogen interaction
ppi-miR529l Upregulated 5.121 unigene116482 Probable RLK Plant–pathogen interaction
ppi-miR946j Upregulated 5.178 isotig75044 Disease resistance RPP13-like protein 4 Plant–pathogen interaction
ppi-miR396j Upregulated 4.923 unigene75931 Disease resistance protein At4g27190-like Plant–pathogen interaction
isotig42452 Bifunctional levopimaradiene synthase (LPS) Diterpenoid biosynthesis
Novel_1871 Upregulated 1.887 unigene31062 Bifunctional abietadiene synthase (AS) Diterpenoid biosynthesis
ppi-miR11436b, f-k, m Upregulated 2.428 (± 1.86) unigene2998 Bifunctional abietadiene synthase (AS) Diterpenoid biosynthesis
Upregulated unigene9633 Bifunctional abietadiene synthase (AS) Diterpenoid biosynthesis
ppi-miR11436b, f-m Upregulated 2.754 (± 2.00) isotig44195 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase Terpenoid backbone biosynthesis
ppi-miRnovel1251 Upregulated 4.890 unigene97227 Bifunctional levopimaradiene synthase (LPS) Monoterpenoid biosynthesis
ppi-miR3627s Upregulated 5.761 isotig56835 Short-chain dehydrogenase/reductase 2b-like Monoterpenoid biosynthesis
ppi-miR11436b, f, g, j, k, m Upregulated 2.725 (± 2.11) isotig34808 Peroxiredoxin Q Cell redox homeostasis
ppi-miR1314f Upregulated 5.123 isotig25066 Peroxiredoxin-2E Cell redox homeostasis
ppi-miR3627l Upregulated 3.980 isotig25066 Peroxiredoxin-2E Cell redox homeostasis
ppi-miR529c, y Upregulated 4.383 (± 2.91) isotig12834 Thioredoxin F-type Cell redox homeostasis
DE miRNAs resistance vs susceptible
ppi-miR166h R > S 6.418 unigene67614 Putative RLK Protein serine/threonine kinase activity
ppi-miR951f R < S  − 1.329 unigene93826 Putative RLK Protein serine/threonine kinase activity
unigene5558 Putative RLK Protein kinase activity
ppi-miR947f R > S 5.163 isotig45349 GDP-L-fucose synthase 2 Amino sugar and nucleotide sugar metabolism
Novel_110 R < S  − 1.550 isotig51371 Protein COBRA-like Cellulose microfibril organization
unigene925 Ninja family protein Signal transduction
ppi-miR3627m R < S  − 3.661 unigene82871 Short-chain dehydrogenase reductase 2a-like Oxidoreductase activity