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. 2022 Feb 21;3(1):R19–R33. doi: 10.1530/RAF-21-0024

Table 1.

Spermicide products containing N-9. Various deliver-9 products with different delivery systems and dosage options of N-9 are shown in the table, together with the directions for use.

Product Form Content Required insert time Instruction Duration Availability
VCF® Film 28% 15 min In contact with the cervix Last for 3 h Available
VCF® Foam 12.5% Less than 1 h; works immediately Insert into vagina; wait at least 6 h for douching Available
VCF® Gel 4% Works immediately Insert into vagina Up to 1 h Available
Gynol II® Gel 3% Works immediately Insert into vagina Up to 1 h Available
Conceptrol® Gel 4% Works immediately Insert into vagina Up to 1 h Available
ContraSeed® Suppository 100 mg 15 min Insert and lie against the cervix Up to 1 h Available
Today® Sponge 1000 mg Works immediately Wet sponge thoroughly and squeeze gently until sudsing; fold with dimple side inside; insert deeply into vagina with string loop on bottom end; wait 6 h before removing and avoid inserting for >30 h 24 h Available
Encare® Suppository 100 mg At least 10 min Insert into vagina; wait at least 6 h for douching Up to 1 h Not available
Advantage 24® Gel 3.5% Less than 30 min Insert into vagina; release steadily in the bioadhesive delivery system attaching to the vaginal epithelial surface 24 h Not available
Shur-Seal® Gel 2% At least 10 min; works immediately Insert into vagina; wait at least 6 h for douching Not available
Delfen® Foam 12.5% Up to 1 h Insert into vagina; wait at least 6 h for douching Not available