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. 2022 Mar 22;27:100783. doi: 10.1016/j.neo.2022.100783

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© 2022 The Authors. Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 1 — Increased DEC1 expression in human and AOM/DSS-induced CRC tissues (A) GEPIA database showed a higher DEC1 expression in human colorectal cancer than that in normal tissues. (B) GEO database showed that patients with low DEC1 expression had a higher survival probability. (C)Multivariate analysis of prognostic factors of colorectal cancer was elucidated based on the GEO. (D) DEC1 in human colorectal cancer by using IHC (N = 10). Scale bar = 40 μm. (E) Schedule of colorectal cancer induced by AOM/DSS in mice. (F) DEC1 expression in AOM/DSS-induced CRC mice through IHC (N = 6 in each group). Scale bar = 40 μm. (G-H) DEC1 protein level in AOM/DSS-induced CRC mice by Western blotting (t-text, t = 4.392, df = 10, p = 0.0014. N = 6 in each group). Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01 vs. normal or solvent.