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LC-DAD fingerprints of Pericarpium Citri Reticulatae was used to exemplify the advantages and disadvantages of (A) PARAFAC2 model, (B) MCR-ALS bilinear, (C) mMSPA-MCR-ALS trilinear and (D) mMSPA-ATLD algorithms. 1: Diosimin; 2: Hesperidin; C3: unknown compound.