Fig. 6.

Nextcast pipeline with multi-view clustering for chemical read-across. Raw omics data can be preprocessed with eUTOPIA. The preprocessed multi-view data for the same samples and/or chemical structure data (e.g. molecular descriptors) can be fed to MVDA to obtain the multi-view cluster assignment of each sample and the influence of each view on the clustering. Red boxes indicate the input while the lighter green boxes mark the output of the pipeline. The dark blue and dark green boxes are the individual Nextcast components, and the light blue boxes correspond to the intermediate output/input.