Figure 1.
Results for the associations between DNA methylation and ischemic stroke. The crude P-values for the associations between DNA methylation and ischemic stroke. The x-axis represents the chromosome positions. The y-axis shows the –log10 P-values for the associations between the levels of DNA methylation sites and ischemic stroke. A total of 866 methylation sites were analyzed in stage one (black circles), and 224 of them passed the significance threshold of 5.75 × 10−5 (red line). A total of 377 methylation sites were analyzed in stage two (green triangles), and 296 of them passed the significance threshold of 5.75 × 10−5. The associated methylation sites tend to cluster in targets.