Table 1.
Characteristics | Stage 1 | Stage 2 | ||||
---|---|---|---|---|---|---|
Cases (n = 271) | Controls (n = 323) | P-values | Cases (n = 852) | Controls (n = 925) | P-values | |
Age, year | 57.3 ± 10.46 | 57.0 ± 10.83 | 0.7238 | 62.5 ± 12.09 | 62.2 ± 12.17 | 0.6632 |
Male, % | 57.34 | 56.43 | 0.8683 | 53.10 | 54.26 | 0.6579 |
Smokers, % | 40.11 | 40.35 | 1.000 | 34.47 | 37.54 | 0.1943 |
Drinkers, % | 35.31 | 24.27 | 0.0019 | 26.03 | 27.29 | 0.5845 |
SBP, mmHg | 173.2 ± 18.88 | 120.2 ± 13.56 | 9.0 × 10−195 | 171.9 ± 17.36 | 137.7 ± 23.20 | 3.9 × 10−203 |
DBP, mmHg | 101.8 ± 11.29 | 72.6 ± 7.98 | 1.6 × 10−178 | 98.9 ± 10.96 | 81.7 ± 11.95 | 1.3 × 10−174 |
Hypertension, % | 100 | 17.5 | 2.9 × 10−72 | 100 | 46.9 | 3.2 × 10−173 |
BMI, kg/m2 | 25.3 ± 3.02 | 21.7 ± 2.77 | 2.5 × 10−49 | 25.1 ± 3.39 | 22.4 ± 3.37 | 2.6 × 10−60 |
TC, mmol/L | 5.14 ± 1.20 | 4.47 ± 0.87 | 6.0 × 10−16 | 5.12 ± 1.16 | 4.67 ± 0.96 | 1.3 × 10−18 |
TG, mmol/L | 1.96 ± 1.29 | 1.33 ± 0.94 | 9.6 × 10−13 | 1.89 ± 4.96 | 1.56 ± 1.14 | 0.0448 |
HDL-C, mmol/L | 1.28 ± 0.53 | 1.40 ± 0.31 | 0.0005 | 1.30 ± 0.41 | 1.34 ± 0.33 | 0.0278 |
LDL-C, mmol/L | 3.01 ± 1.07 | 2.49 ± 0.71 | 3.7 × 10−13 | 2.94 ± 0.98 | 2.66 ± 0.78 | 8.2 × 10−13 |
FBG, mmol/L | 6.89 ± 2.75 | 5.07 ± 0.64 | 7.8 × 10−30 | 6.78 ± 2.82 | 5.03 ± 1.17 | 4.6 × 10−62 |
Type 2 diabetes, % | 17.0 | 0 | 5.0 × 10−14 | 19.4 | 2.9 | 1.6 × 10−28 |
Compared with the controls, the mean BMI, SBP, DBP, TC, LDL-C, TG and GLU levels were all higher, while HDL-C level was lower in ischemic stroke patients in both stages.