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. 2022 Mar 8;9:796245. doi: 10.3389/fcvm.2022.796245

Table 1.

Characteristics of the ischemic stroke cases and controls.

Characteristics Stage 1 Stage 2
Cases (n = 271) Controls (n = 323) P-values Cases (n = 852) Controls (n = 925) P-values
Age, year 57.3 ± 10.46 57.0 ± 10.83 0.7238 62.5 ± 12.09 62.2 ± 12.17 0.6632
Male, % 57.34 56.43 0.8683 53.10 54.26 0.6579
Smokers, % 40.11 40.35 1.000 34.47 37.54 0.1943
Drinkers, % 35.31 24.27 0.0019 26.03 27.29 0.5845
SBP, mmHg 173.2 ± 18.88 120.2 ± 13.56 9.0 × 10−195 171.9 ± 17.36 137.7 ± 23.20 3.9 × 10−203
DBP, mmHg 101.8 ± 11.29 72.6 ± 7.98 1.6 × 10−178 98.9 ± 10.96 81.7 ± 11.95 1.3 × 10−174
Hypertension, % 100 17.5 2.9 × 10−72 100 46.9 3.2 × 10−173
BMI, kg/m2 25.3 ± 3.02 21.7 ± 2.77 2.5 × 10−49 25.1 ± 3.39 22.4 ± 3.37 2.6 × 10−60
TC, mmol/L 5.14 ± 1.20 4.47 ± 0.87 6.0 × 10−16 5.12 ± 1.16 4.67 ± 0.96 1.3 × 10−18
TG, mmol/L 1.96 ± 1.29 1.33 ± 0.94 9.6 × 10−13 1.89 ± 4.96 1.56 ± 1.14 0.0448
HDL-C, mmol/L 1.28 ± 0.53 1.40 ± 0.31 0.0005 1.30 ± 0.41 1.34 ± 0.33 0.0278
LDL-C, mmol/L 3.01 ± 1.07 2.49 ± 0.71 3.7 × 10−13 2.94 ± 0.98 2.66 ± 0.78 8.2 × 10−13
FBG, mmol/L 6.89 ± 2.75 5.07 ± 0.64 7.8 × 10−30 6.78 ± 2.82 5.03 ± 1.17 4.6 × 10−62
Type 2 diabetes, % 17.0 0 5.0 × 10−14 19.4 2.9 1.6 × 10−28

Compared with the controls, the mean BMI, SBP, DBP, TC, LDL-C, TG and GLU levels were all higher, while HDL-C level was lower in ischemic stroke patients in both stages.