Table3.

Univariate analyses of biomarkers for OS and PFS

Characteristic	Reference	OS			PFS
		HR	95% CI	p value	HR	95% CI	p value
Sex	Male	2.44	1.59–3.75	< 0.001	2.26	1.51–3.40	< 0.001
Age		1.01	0.99–1.03	0.241	1.01	0.99–1.03	0.257
Smoking	Yes	1.69	1.16–2.46	0.007	1.53	1.07–2.20	0.021
Pathology	Adeno
	Another	1.73	0.85–3.51	0.128	1.7	0.87–3.32	0.122
	SCLC	2.86	1.49–5.47	0.002	2.53	1.33–4.81	0.005
	Squama	1.96	1.29–3.00	0.002	1.82	1.21–2.75	0.004
Size		1.01	0.99–1.02	0.327	1.01	1.00–1.02	0.262
PIS	Yes	1.78	1.20–2.64	0.004	1.96	1.35–2.85	< 0.001
TNM	II	1.25	0.86–1.83	0.238	1.32	0.92–1.89	0.133
BMI		0.97	0.92–1.03	0.369	0.98	0.93–1.04	0.527
MLR	Low	0.39	0.27–0.57	< 0.001	0.43	0.30–0.61	< 0.001
NLR	Low	0.46	0.31–0.70	< 0.001	0.49	0.33–0.72	< 0.001
PLR	Low	0.57	0.39–0.83	0.004	0.64	0.44–0.91	0.014
D-Dimer	Low	0.4	0.24–0.67	< 0.001	0.57	0.37–0.89	0.013
ECGO PS	0–1	0.26	0.18–0.39	< 0.001	0.21	0.14–0.31	< 0.001