Table 4.

Multivariate analyses of biomarkers for OS and PFS

Characteristic	Reference	OS			PFS
		HR	95% CI	p value	HR	95% CI	p value
Sex	male	1.72	1.06–2.80	0.0284	1.51	0.96–2.39	0.0773
Pathology	Adeno
	Another	1.41	0.69–2.90	0.3449	1.47	0.75–2.91	0.2652
	SCLC	2.25	1.14–4.44	0.0189	2.44	1.26–4.72	0.0083
	Squama	1.56	0.98–2.46	0.0582	1.61	1.03–2.51	0.0379
PIS	yes	1.48	0.97–2.28	0.0697	1.61	1.07–2.40	0.0218
MLR	low	0.56	0.37–0.87	0.0092	0.57	0.39–0.85	0.0055
PLR	low	0.74	0.49–1.12	0.1575
D-Dimer	low	0.48	0.29–0.80	0.0054	0.67	0.43–1.04	0.0766
ECGO PS	0–1	0.28	0.18–0.42	< 0.0001	0.23	0.15–0.34	< 0.0001