Table 3.

Multivariate analysis of factors associated with overall survival.

Multivariate analysis	OS (n=167)		RFS (n=167)
Variable	HR (95% CI)	p value*	HR (95% CI)	p value*
T stage
T1	Ref.		Ref.
T2	2.037 (0.740-5.604)	0.202	1.009 (0.534-1.908)	0.977
T3	2.597 (1.070-6.303)	0.053	0.773 (0.432-1.384)	0.581
Node metastasis
N0 vs. N+	1.284 (0.458-3.596)	0.635	0.924 (0.223-3.837)	0.977
TNM stage
I +II vs. III+IV	8.539 (2.144-34.013)	0.004	4.992 (1.054-23.649)	0.086
Histologic Grade
Well vs. Poor-	0.408 (0.246-0.679)	0.002	0.469 (0.303-0.724)	0.001
TCF7
Low vs. High	0.235 (0.133-0.414)	<0.001	2.661 (1.675-4.227)	<0.001

HR, hazard ratio; CI, confidence interval.

p value*: Multiple test correction by the “Benjamini & Hochberg” (BH) method.