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. 2022 Mar 8;13:820508. doi: 10.3389/fphar.2022.820508

TABLE 3.

Twenty-one hub pathways across the three groups.

Term ID PTZ vs. Con. Q808 vs. PTZ
p-value Enrichment score p-value Enrichment score
VEGF signaling pathway rno04370 0.002 5.985 0.032 3.581
Basal cell carcinoma rno05217 0.002 5.593 0.036 3.346
Ether lipid metabolism rno00565 0.008 4.944 0.021 4.437
Malaria rno05144 0.012 4.135 0.000 14.844
Toxoplasmosis rno05145 0.015 3.130 0.016 3.745
Graft-versus-host disease rno05332 0.019 3.499 0.040 3.140
Amphetamine addiction rno05031 0.020 3.446 0.041 3.092
Leishmaniasis rno05140 0.021 3.394 0.042 3.046
Renin secretion rno04924 0.022 3.345 0.044 3.002
Allograft rejection rno05330 0.022 3.345 0.044 3.002
Asthma rno05310 0.023 4.212 0.008 7.559
Bile secretion rno04976 0.024 3.203 0.047 2.875
Focal adhesion rno04510 0.029 2.309 0.003 4.144
Human papillomavirus infection rno05165 0.030 2.001 0.006 2.993
Rheumatoid arthritis rno05323 0.037 2.707 0.008 4.860
Fluid shear stress and atherosclerosis rno05418 0.038 2.353 0.034 2.815
Renin–angiotensin system rno04614 0.040 3.159 0.013 5.670
Viral myocarditis rno05416 0.042 2.584 0.009 4.639
GnRH signaling pathway rno04912 0.043 2.555 0.009 4.587
Glycine, serine, and threonine metabolism rno00260 0.044 2.992 0.015 5.371
Bladder cancer rno05219 0.048 2.843 0.016 5.103