Table 1.

Equilibrium solubility of ketoconazole base at different pH at 25 °C, where pH of aqueous suspensions was lowered using HCl solutions. pH and corresponding solubilities from individual vials, including repeating observations, are shown.

pH of suspension	Solubility (μg/mL)		pH of suspension	Solubility (μg/mL)		pH of suspension	Solubility (μg/mL)
3.1	148320		4.28	729		7.23	4
3.35	5457		4.48	345		7.23	4
3.35	5429		4.56	354		7.27	3
3.37	7100		4.56	354		7.72	2
3.58	3425		4.95	178		7.92	3
3.67	3031		4.99	175		8.49	2
3.71	2782		4.99	175
3.81	1931		7.12	5