FIG. 3.

(a) Rates computed by InfrMetaD for the potential in Fig. 1(b) with forces given in pN and rates in μs⁻¹. This system exhibits catch-slip bond behavior, and the rate dependence can be fit well to a catch-slip rate dependence (dashed line) as described in the main text. (b) The free energy barrier in the y direction computed from data in Fig. 4 using Eq. (6) shows an increase and decrease with force mostly commensurate with the rate dependence.