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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Spine J. 2021 Oct 27;22(4):677–689. doi: 10.1016/j.spinee.2021.10.014

Figure 8. Lateral disc puncture with nerve exposure induced increased Iba1+ macrophages/microglia in the ipsilateral spinal nerves.

Figure 8.

(a) Immunostaining of axial spine sections showed abundant Iba1+ macrophages in the ipsilateral nervescompared to the contralateral nerve on POD 7. Black arrows point to nerves. Scale bar=50 μm. (b) Quantitative analysis showed more than a 2-fold increase in Iba1+ cells in the ipsilateral nerve vs. the contralateral side. **p<0.01, n=3 per group, unpaired t-test.