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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Free Radic Biol Med. 2022 Feb 17;182:23–33. doi: 10.1016/j.freeradbiomed.2022.02.006

Figure 7. Abnormal mitochondria and ferroptosis related oxidative damages in cortical neurons of MPAN brain.

Figure 7.

(A) Representative confocal images of mitochondrial after immunostaining with anti-OXPHOS cocktail antibodies in pyramidal neurons in C19orf12T11M MPAN cortical tissues. Right, quantification of mitochondrial length and neurite mitochondrial index in neurons (n = 16 neurons). (B-D) Representative immunohistochemistry images of staining with anti-HMOX1 antibodies (B), anti-8OHG antibodies (C) and anti-HNE antibodies (D) in C19orf12T11M MPAN cortex sections (n = 60 cells). Results are representative data (Means ± SE) of three independent experiments (n = 3 replicates). Student’s t test, *** P < 0.001.