Table 1.
RA patient information between TNF inhibitor treatment and non-treatment group after propensity score matching - adult patients
| VARIABLE | NON-TNF INHIBITOR | TNF INHIBITOR | P VALUE | SMD |
|---|---|---|---|---|
| N | 5016 | 2510 | ||
| AGE (SD) | 66.43 (13.92) | 65.59 (13.35) | 0.012 | 0.062 |
| GENDER= M (%) | 4337 (86.5) | 2147 (85.5) | 0.289 | 0.027 |
| RACE (%) | 0.205 | 0.043 | ||
| White | 3745 (74.7) | 1854 (73.9) | ||
| Black | 790 (15.7) | 383 (15.3) | ||
| Other | 481 (9.6) | 273 (10.9) | ||
| REGION (%) | 0.989 | 0.008 | ||
| Midwest | 1341 (26.7) | 665 (26.5) | ||
| Northeast | 470 (9.4) | 232 (9.2) | ||
| South | 2186 (43.6) | 1097 (43.7) | ||
| West | 1019 (20.3) | 516 (20.6) | ||
| RURALITY = Urban (%) | 3114 (62.1) | 1580 (62.9) | 0.48 | 0.018 |
| MARRIGE (%) | 0.675 | 0.043 | ||
| Married | 3042 (60.6) | 1486 (59.2) | ||
| Divorced | 1074 (21.4) | 543 (21.6) | ||
| Separated | 156 (3.1) | 83 (3.3) | ||
| Single | 452 (9.0) | 253 (10.1) | ||
| Widowed | 259 (5.2) | 126 (5.0) | ||
| Unknown | 33 (0.7) | 19 (0.8) | ||
| COMORIDITIES | ||||
| Alcohol use = 1 (%) | 147 (2.9) | 70 (2.8) | 0.784 | 0.009 |
| Anxiety = 1 (%) | 311 (6.2) | 145 (5.8) | 0.5 | 0.018 |
| Depression = 1 (%) | 375 (7.5) | 168 (6.7) | 0.234 | 0.031 |
| Obesity (%) | 0.41 | 0.033 | ||
| Normal | 1067 (21.3) | 567 (22.6) | ||
| Obesity | 2214 (44.1) | 1082 (43.1) | ||
| Overweight | 1735 (34.6) | 861 (34.3) | ||
| Diabetes (%) | 599 (11.9) | 293 (11.7) | 0.763 | 0.008 |
| Hypertension (%) | 1496 (29.8) | 744 (29.6) | 0.891 | 0.004 |
| Peripheral vascular disease (%) | 129 (2.6) | 69 (2.7) | 0.707 | 0.011 |
| Cardiovascular disease (%) | 574 (11.4) | 289 (11.5) | 0.958 | 0.002 |
| Hyperlipidemia (%) | 1276 (25.4) | 631 (25.1) | 0.8 | 0.007 |
| Traumatic Brain Injury (%) | 283 (5.6) | 150 (6.0) | 0.593 | 0.014 |
| DRUG USE | ||||
| Methotrexate (%) | 3766 (75.1) | 1844 (73.5) | 0.137 | 0.037 |
| Sulfasalazine (%) | 1434 (28.6) | 761 (30.3) | 0.126 | 0.038 |
| Leflunomide (%) | 1099 (21.9) | 577 (23.0) | 0.303 | 0.026 |
| Hydroxychloroquine (%) | 2218 (44.2) | 1116 (44.5) | 0.86 | 0.005 |
| Prednisone (%) | 3885 (77.5) | 1907 (76.0) | 0.16 | 0.035 |
| NSAID (%) | 4208 (83.9) | 2101 (83.7) | 0.862 | 0.005 |
| Follow-Up days (SD) | 5049.70 (1880.52) | 5005.89 (1881.94) | 0.341 | 0.023 |
| Charlson Index (SD) | 0.57 (0.90) | 0.57 (0.95) | 0.768 | 0.007 |
SMD: standardized mean difference.