Table 2.
RA patient information between TNF inhibitor treatment and non-treatment group after propensity score matching - elderly patients (> 65 years old)
| VARIABLE | NON-TNF INHIBITOR | TNF INHIBITOR | P VALUE | SMD |
|---|---|---|---|---|
| N | 1616 | 817 | ||
| AGE (SD) | 71.39 (5.27) | 71.33 (5.09) | 0.799 | 0.011 |
| GENDER= M (%) | 1557 (96.3) | 784 (96.0) | 0.718 | 0.02 |
| RACE (%) | 0.972 | 0.01 | ||
| White | 1267 (78.4) | 644 (78.8) | ||
| Black | 103 (6.4) | 51 (6.2) | ||
| Other | 246 (15.2) | 122 (14.9) | ||
| REGION (%) | 0.911 | 0.031 | ||
| Midwest | 447 (27.7) | 230 (28.2) | ||
| Northeast | 194 (12.0) | 102 (12.5) | ||
| South | 621 (38.4) | 316 (38.7) | ||
| West | 354 (21.9) | 169 (20.7) | ||
| RURALITY = Urban (%) | 932 (57.7) | 475 (58.1) | 0.86 | 0.009 |
| MARRIGE (%) | 0.989 | 0.033 | ||
| Married | 1160 (71.8) | 585 (71.6) | ||
| Divorced | 216 (13.4) | 109 (13.3) | ||
| Separated | 32 (2.0) | 17 (2.1) | ||
| Single | 60 (3.7) | 30 (3.7) | ||
| Widowed | 134 (8.3) | 71 (8.7) | ||
| Unknown | 14 (0.9) | 5 (0.6) | ||
| COMORIDITIES | ||||
| Alcohol use = 1 (%) | 44 (2.7) | 24 (2.9) | 0.862 | 0.013 |
| Anxiety = 1 (%) | 46 (2.8) | 25 (3.1) | 0.867 | 0.013 |
| Depression = 1 (%) | 55 (3.4) | 24 (2.9) | 0.623 | 0.027 |
| Obesity (%) | 0.841 | 0.025 | ||
| Normal | 345 (21.3) | 181 (22.2) | ||
| Obesity | 649 (40.2) | 319 (39.0) | ||
| Overweight | 622 (38.5) | 317 (38.8) | ||
| Diabetes (%) | 250 (15.5) | 128 (15.7) | 0.946 | 0.005 |
| Hypertension (%) | 508 (31.4) | 268 (32.8) | 0.524 | 0.029 |
| Peripheral vascular disease (%) | 53 (3.3) | 25 (3.1) | 0.866 | 0.013 |
| Cardiovascular disease (%) | 304 (18.8) | 163 (20.0) | 0.536 | 0.029 |
| Hyperlipidemia (%) | 452 (28.0) | 228 (27.9) | 1 | 0.001 |
| Traumatic Brain Injury (%) | 59 (3.7) | 34 (4.2) | 0.611 | 0.026 |
| DRUG USE | ||||
| Methotrexate (%) | 1164 (72.0) | 579 (70.9) | 0.581 | 0.026 |
| Sulfasalazine (%) | 390 (24.1) | 213 (26.1) | 0.319 | 0.045 |
| Leflunomide (%) | 362 (22.4) | 189 (23.1) | 0.722 | 0.017 |
| Hydroxychloroquine (%) | 653 (40.4) | 331 (40.5) | 0.995 | 0.002 |
| Prednisone (%) | 1162 (71.9) | 598 (73.2) | 0.533 | 0.029 |
| NSAID (%) | 1168 (72.3) | 590 (72.2) | 1 | 0.001 |
| Follow-Up days (SD) | 5133.54 (1860.10) | 5166.65 (1838.35) | 0.583 | 0.018 |
| Charlson Index (SD) | 0.70 (0.95) | 0.71 (1.02) | 0.868 | 0.007 |