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. Author manuscript; available in PMC: 2023 Jul 15.
Published in final edited form as: Biol Psychiatry. 2021 Sep 27;92(2):127–138. doi: 10.1016/j.biopsych.2021.09.017

Figure 1. THC treatment in utero leads to enduring behavioral alterations in adult offspring.

Figure 1.

(A) Prenatal THC Paradigm. Pregnant females were treated with low dose THC or VEH and offspring were studied at adulthood. Food Self-administration under (B) Fixed Ratio 1 (FR1) and (C) Progressive Ratio (PR) schedules. (D) Immobility behavior in the Forced Swim Test (FST). (E) Preference of 1% sucrose solution over water. Horizontal line and asterisk indicate a significant interaction effect between PTE and FST. N=7–9/group in all behavioral tests. Data are expressed as mean ± SEM. *:p<0.05.