Skip to main content
. Author manuscript; available in PMC: 2022 Mar 27.
Published in final edited form as: J Alzheimers Dis. 2017;59(2):743–751. doi: 10.3233/JAD-170298

Fig. 2.

Fig. 2.

Tau oligomers do not alter the phosphorylation state of tau protein. Representative western blot of brain extracts (20 μg protein) from mice injected with control ACSF solution or tau peptides (ICV for 3 h) using antibodies specific for the detection of four pathological tau phosphorylation sites: AT8, pS396, pS262, and pS422. An antibody raised against GAPDH served as a loading control. Densitometric quantification shows that both oTau and mTau were not able to alter the phosphorylation state of tau. The data are mean ± SEM, n = 6.