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. 2013 Mar 28;2013(3):CD004559. doi: 10.1002/14651858.CD004559.pub4

Comparison 1. Traditional Chinese medicine (TCM) versus other treatments.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Recovery 8   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
1.1 Fanggan decoction versus conventional medicine 1 95 Risk Ratio (M‐H, Random, 95% CI) 1.02 [0.67, 1.56]
1.2 Fever resolved within 24 hours after treatment (Lianhua Qingwen capsule versus oseltamivir) 1 145 Risk Ratio (M‐H, Random, 95% CI) 0.95 [0.66, 1.38]
1.3 Fever resolved within 24 hours after treatment (Lianhua Qingwen capsule versus control 2) 1 145 Risk Ratio (M‐H, Random, 95% CI) 1.91 [1.03, 3.52]
1.4 Ganmao capsule versus amantadine 1 738 Risk Ratio (M‐H, Random, 95% CI) 0.48 [0.38, 0.61]
1.5 Ganmao capsule versus amantadine (Day 2) 1 432 Risk Ratio (M‐H, Random, 95% CI) 5.17 [3.82, 6.99]
1.6 E Shu You versus ribavirin (Day 3) 1 61 Risk Ratio (M‐H, Random, 95% CI) 2.18 [0.87, 5.43]
1.7 Tanreqing + oseltamivir versus oseltamivir 2 197 Risk Ratio (M‐H, Random, 95% CI) 1.32 [0.87, 2.00]
1.8 TCM versus oseltamivir 1 60 Risk Ratio (M‐H, Random, 95% CI) 1.13 [0.50, 2.52]
1.9 Antiwei versus placebo (day 4) 1 225 Risk Ratio (M‐H, Random, 95% CI) 3.80 [1.23, 11.72]
2 Time to fever clearance 10   Mean Difference (IV, Fixed, 95% CI) Totals not selected
2.1 TCM versus oseltamivir 3   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.2 Gegeng Tang granule + oseltamivir versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.3 Lianhua Qingwen capsule versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.4 TCM + oseltamivir versus oseltamivir 3   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.5 Tanreqing injection + oseltamivir versus oseltamivir 2   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.6 Fanggan granule versus conventional medicine 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
3 Duration of cough 4   Mean Difference (IV, Fixed, 95% CI) Totals not selected
3.1 Fanggan decoction versus conventional medicine 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.2 Ge Geng Tang granule + oseltamivir versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.3 Tanreqing injection + oseltamivir versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.4 TCM versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
4 Time to remission of muscle pain 2   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.1 Lianhua Qingwen capsule 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.2 TCM versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
5 Time to symptom remission 4   Mean Difference (IV, Fixed, 95% CI) Totals not selected
5.1 TCM versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
5.2 Fanggan granule versus conventional medicine 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
5.3 Gegeng Tang granule + oseltamivir versus oseltamivir (body pain) 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
5.4 TCM + oseltamivir versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
6 Time to remission of sore throat 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
6.1 TCM versus oseltamivir 1 60 Mean Difference (IV, Fixed, 95% CI) ‐15.60 [‐17.87, ‐13.33]
7 Length of hospital stay 4   Mean Difference (IV, Fixed, 95% CI) Totals not selected
7.1 TCM versus oseltamivir 2   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
7.2 Tanreqing injection + oseltamivir versus oseltamivir 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
7.3 TCM plus oseltamivir versus oseltamivir 2   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
7.4 TCM versus placebo 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
8 No improvement or worsening influenza 7   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
8.1 E Shu You versus ribavirin (Day 3) 1 61 Risk Ratio (M‐H, Random, 95% CI) 0.40 [0.14, 1.17]
8.2 Fanggan decoction versus conventional medicines 1 95 Risk Ratio (M‐H, Random, 95% CI) 0.70 [0.24, 2.05]
8.3 Tanreqing injection + oseltamivir versus oseltamivir 2 197 Risk Ratio (M‐H, Random, 95% CI) 0.37 [0.17, 0.80]
8.4 TCM versus oseltamivir 1 60 Risk Ratio (M‐H, Random, 95% CI) 2.0 [0.19, 20.90]
8.5 Lianhua Qingwen versus oseltamivir 1 145 Risk Ratio (M‐H, Random, 95% CI) 1.0 [0.22, 4.46]
8.6 Lianhua Qingwen versus Anga huangmin 1 145 Risk Ratio (M‐H, Random, 95% CI) 0.20 [0.09, 0.46]
8.7 Ganmao capsule versus amantadine 1 951 Risk Ratio (M‐H, Random, 95% CI) 0.15 [0.10, 0.21]
9 Partial improvement 6 703 Risk Ratio (M‐H, Random, 95% CI) 1.05 [0.82, 1.36]
9.1 Tanreqing injection + oseltamivir 1 110 Risk Ratio (M‐H, Random, 95% CI) 0.6 [0.23, 1.54]
9.2 Fanggan granule versus Western medicine 1 95 Risk Ratio (M‐H, Random, 95% CI) 1.09 [0.66, 1.78]
9.3 Lianhua Qingwen versus oseltamivir 1 145 Risk Ratio (M‐H, Random, 95% CI) 1.2 [0.50, 2.87]
9.4 Lianhua Qingwen capsule versus An ga huang min 1 145 Risk Ratio (M‐H, Random, 95% CI) 1.2 [0.50, 2.87]
9.5 Tanreqing + oseltamivir versus oseltamivir 1 87 Risk Ratio (M‐H, Random, 95% CI) 1.29 [0.84, 1.96]
9.6 TCM versus oseltamivir 1 60 Risk Ratio (M‐H, Random, 95% CI) 0.44 [0.15, 1.29]
9.7 E Shu You versus ribavirin 1 61 Risk Ratio (M‐H, Random, 95% CI) 0.91 [0.36, 2.27]
10 Adverse events 10 1011 Risk Ratio (M‐H, Random, 95% CI) 0.54 [0.26, 1.11]
10.1 TCM versus oseltamivir 3 154 Risk Ratio (M‐H, Random, 95% CI) 1.12 [0.04, 32.35]
10.2 Lianhua Qingwen versus oseltamivir 3 241 Risk Ratio (M‐H, Random, 95% CI) 0.34 [0.11, 1.02]
10.3 Fanggan granule versus conventional medicine 1 95 Risk Ratio (M‐H, Random, 95% CI) 0.98 [0.14, 6.67]
10.4 Antiwei versus placebo 1 225 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
10.5 Tanreqing plus oseltamivir versus oseltamivir 1 87 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
10.6 E Shu You versus Lymbaweilim 1 61 Risk Ratio (M‐H, Random, 95% CI) 0.60 [0.11, 3.36]
10.7 Lianhua Qingwen versus An ga huang min 1 148 Risk Ratio (M‐H, Random, 95% CI) 0.73 [0.08, 6.78]