Zheng 2010b.
Methods | Participants were allocated by drawing lots, but no detailed information about blinding given | |
Participants | Participants with fever (temperature higher than 37.8 degrees) and with typical symptoms of influenza, diagnosed by a positive finding of real‐time RT‐PCR test in throat swabs. The eligible participants had no history of administration of any medicine in past 48 hours. The symptoms of influenza had lasted over 48 hours and within 72 hours Participants were allocated into 3 groups: 19 in the oseltamivir group, 14 in the TCM treatment group and 15 in the oseltamivir and TCM treatment group |
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Interventions | TCM versus oseltamivir versus TCM combined with oseltamivir | |
Outcomes | 1. Total course of disease 2. Duration of flu symptoms (except cough) 3. Time until A/H1N1 virus disappeared 4. Symptom remission time of fever 5. Symptom remission time of cough |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Allocated patients by drawing lots |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Unclear |
Selective reporting (reporting bias) | Unclear risk | Unclear |
Other bias | Unclear risk | Unclear |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |