Figure 2. Merged analysis of same-sex human pituitaries.
(A–E) UMAP representation of sn transcript expression (A, males; C, females) and of sn chromatin accessibility (B, males; D, females) in the merged same-sex samples, with labeling by donor age in each sex, and transcriptome by individual assays performed on the same donor. (E) Individual donors (A–E) or assays for a same donor (E) are color-coded as indicated. Each cluster is identified by a letter code as defined in Figure 1.
(F) Donor-related information is provided in see Table 1. Correlation between the cell type proportions identified by snRNA-seq versus snATAC-seq for all samples (males and females). Assays done for the pediatric sample in (F) were done on different days. The linear regression is plotted. Pituitary cell types are color-coded and the key is provided underneath the plot.
