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. 2021 Jun 24;36(4):473–481. doi: 10.46497/ArchRheumatol.2021.8364

Table 4. Analysis of factors affecting biological treatment process.

  Continued as it was before Stopped all of the medications Stopped only biological and synthetic therapy Decreased or skipped the dose of biological therapy p
n % n % n % n %
Working status                 0.983
Employed 104 63.8 20 12.3 15 9.2 24 (14.7) 14.7  
Unemployed 4 80.0 0 0 0 0 1 (20.0) 20.0  
Housewife 37 68.5 6 11.1 4 7.4 7 (13.0) 13.0  
Retired 33 67.3 7 14.3 3 6.1 6 (12.2) 12.2  
Need to go out for work                 0.135
Unable to go to work 75 69.4 13 12.0 8 7.4 12 (11.1) 11.1  
due to pandemic Be able to go to work 29 52.7 7 12.7 7 12.7 12 (21.8) 21.8  
Comorbid disease                  
No comorbidity 126 68.9 19 10.4 11 6.0 27 14.8 0.130
Hypertension 32 66.7 4 8.3 4 8.3 8 16.7 0.799
Diabetes mellitus 10 58.8 3 17.6 3 17.6 1 5.9 0.326
Cardiovascular disease 11 78.6 1 7.1 2 14.3 0 0 0.328
Pulmonary disease 3 60.0 2 40.0 0 0 0 0 0.222
Smoking status                 0.855
Active 66 67.3 11 11.2 6 6.1 15 15.3  
Quit 44 68.8 8 12.5 4 6.3 8 12.5  
Never 68 63.0 14 13.0 12 11.1 14 13.0  
Rheumatic diseases                 0.096
Spondyloarthritis 148 65.5 31 13.7 15 6.6 32 14.2  
Rheumatoid arthritis 30 66.7 2 4.4 7 15.6 6 13.3  
Medications                 0.731
Anti-tumor necrosis factor 161 66.8 28 11.6 19 7.9 33 13.7  
Non-TNF biological DMARDs 17 56.7 5 16.7 3 10.0 5 16.7  
Receiving infusion therapy                 0.001*
Yes 24 44.4 8 14.8 7 13.0 15 27.8  
No 153 70.8 25 11.6 15 6.9 23 10.6  
History of contact with                  
COVID-19 patients 8 50.0 5 31.3 1 6.3 2 12.5 0.121
Yes 178 66.7 28 11.0 21 8.2 36 14.1  
No                  
Diagnosed with COVID-19                 0.221
Yes 1 33.3 1 33.3 1 33.3 0 0  
No 177 66.0 32 11.9 21 7.8 38 14.2  
TNF: Tumor necrosis factor; DMARDs: Disease-modifying anti-rheumatic drugs; * p<0.05, Chi-square test.