TABLE 5.

Description of the key characteristics of genome-scale metabolic networks and graphs.

Main characteristics of genome-scale metabolic networks and graphs
Nodes	A “pool” of compounds (not restricted to small molecules)
Edges	Substrate-product relationships from known reactions
Main Hypothesis	Using genome annotation, reaction databases, and manual/semi-auto curation to generate a model of an organism’s metabolism
Limitations	There are gaps in the knowledge or predicted metabolic reactions in organisms, which creates an incomplete network of the metabolism