Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 8;13:787884. doi: 10.3389/fgene.2022.787884

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zhou, Yang, Cui, Lu, Huang, Che, Yang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Verification of expression and prognosis of three target genes (BNIP3, RRM2, and GOT1) from the GEPIA, UALCAN, and K-M Plotter databases. BNIP3 and RRM2 were significantly upregulated in ccRCC tissues, but GOT1 was significantly downregulated in ccRCC tissues (A-C). The expression levels of BNIP3 and GOT1 decreased gradually with the increase of grades, but RRM2 increased gradually with the increase of grades and stages (D-I). The high expression levels of RRM2 and low expression levels of BNIP3 and GOT1 were associated with poor prognosis (J-O). Linear correlation analysis found that RRM2, BNIP3, and GOT1 may be potential target genes of LINC00460, LINC01550, and EPB41L4A-DT, respectively (P-R).