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. 2022 Mar 8;13:787884. doi: 10.3389/fgene.2022.787884

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Copyright © 2022 Zhou, Yang, Cui, Lu, Huang, Che, Yang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Estimation of the clinical value of the FRlncRNA signature in ccRCC patients. The univariate Cox regression analysis showed that risk score and clinicopathological features including gender, age, grade, stage, T stage, N stage, and M stage were prognostic-related variables (A). The multivariate Cox regression analysis showed the risk score was an independent prognostic factor (B). Construction of a prognostic nomogram based on the risk score and clinicopathological parameters to predict 1-, 3-, 5-year OS of ccRCC patients (C). The multivariate ROC curve showed predictive accuracy of the risk score was similar to other clinicopathological features (D). The calibration curves of the nomogram displayed the concordance between predicted and observed 1-, 3-, and 5-year OS (E).