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. 2022 Mar 8;13:797589. doi: 10.3389/fimmu.2022.797589

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Copyright © 2022 Tada, Zhou, Samanovic, Dcosta, Cornelius, Herati, Mulligan and Landau

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neutralization of variant spike protein pseudotyped viruses by Regeneron antibodies. Neutralization of Beta, Delta, Delta plus and Lambda variant spike protein variants by REGN10933 and REGN10987 monoclonal antibodies. Neutralization of D614G and variant pseudotyped viruses by REGN10933 (left), REGN10987 (middle), and 1:1 ratio of REGN10933 and REGN10987 (right). The IC₅₀ values of REGN10933, REGN10987 and the cocktail is shown in the table.