TABLE 3.
The insulin sensitivity factors (ISF) and the insulin sensitivity constants (calculated as the ISF in mg/dL × total daily insulin dose in units/day) for the study participants.
| All participants (n = 93) | Participants using insulin degludec 100 Units/mL (n = 49) |
Participants using insulin glargine 300 Units/mL (n = 44) |
p-value | |
| The “1800” rule-calculated ISF (in mg/dL), median (IQR) | 56.3 (36-72) | 56.2 (35.3-64.3) | 58.1 (36.3-77.4) | 0.45 |
| Real-life morning ISF (in mg/dL), median (IQR) | 50 (40-75) | 50 (40-60) | 60 (40-75) | 0.53 |
| Real-life afternoon ISF (in mg/dL), median (IQR) | 60 (40-75) | 60 (40-75) | 60 (40-78.8) | 0.38 |
| Real-life evening ISF (in mg/dL), median (IQR) | 75 (45-77.5) | 75 (40-75) | 75 (50-80) | 0.47 |
| Morning insulin sensitivity constant, median (IQR) | 1800 (1680-1920) | 1800 (1680-1922.5) | 1780 (1620-1915) | 0.47 |
| Afternoon insulin sensitivity constant, median (IQR) | 1920 (1800-2075) | 1920 (1800-2032) | 1910 (1760-2100) | 0.98 |
| Evening insulin sensitivity constant, median (IQR) | 2100 (1920-2250) | 2100 (1965-2275) | 2100 (1905-2250) | 0.55 |
ISF, insulin sensitivity factor; IQR, interquartile range.