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. 2022 Mar 8;13:814855. doi: 10.3389/fmicb.2022.814855

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Copyright © 2022 Wang, Wu, Zhou, Qiu, Zhang, Tu, Zhou, Shao, Xu, Wang and Tao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BBR Inhibited TMAO Synthesis in Ang II-Induced Hypertensive Mice. (A) Plasma TMA level of each group (n = 5). (B) Plasma TMAO level of each group (n = 5). (C) Western blotting detection of FMO3 expression in the liver. (D) Statistical analysis of hepatic FMO3 expression of each group (n = 4). (E) Linear correlation between TMAO level and PWV, media thickness of aorta, SBP and endothelium dependent vasodilation (n = 10). *p < 0.05.