Table 1.
Frequency table of community state type (CST) groupings at each visit for placebo and tenofovir/levonorgestrel intravaginal ring users (cyclic and continuous dosing cohorts combined).
| Month (Visit) | Lactobacillus dominated microbiota (CST I, II, III, V) | Anaerobic, diverse microbiota (CST IVA and IVB) | p value baseline versus each month |
|---|---|---|---|
| TFV/LNG IVR (cyclic and continuous dosing regimens combined) | |||
| Baseline (Visit 4) | 18 | 18 | REF |
| Month 1 (Visit 13) | 17 | 14 | 1.0 |
| Month 2 (Visit 22) | 16 | 13 | 0.86 |
| Month 3 (Visit 31) | 20 | 11 | 0.87 |
| Placebo IVR (cyclic and continuous dosing regimens combined) | |||
| Baseline (Visit 4) | 4 | 6 | REF |
| Month 1 (Visit 13) | 5 | 5 | 1.0 |
| Month 2 (Visit 22) | 4 | 6 | 0.75 |
| Month 3 (Visit 31) | 5 | 5 | 1.0 |