Table 2.
Demographic differences between participants based on high versus expected in vivo TFV release rates.
| Variable | Expected in vivo TFV release | High in vivo TFV release | p value |
|---|---|---|---|
| N (%) | N (%) | ||
| Race | 0.02 | ||
| American Indian | 0 | 1 (5.9) | |
| Asian | 0 | 1 (5.9) | |
| Black | 5 (27.8) | 2 (11.8) | |
| Mixed | 6 (33.3) | 12 (70.9) | |
| White | 7 (38.9) | 1 (38.9) | |
| Ethnicity | 0.04 | ||
| Hispanic | 7 (38.9) | 13 (76.5) | |
| Non-Hispanic | 11 (61.1) | 4 (23.5) | |
| Research site | 0.05 | ||
| Dominican Republic | 6 (31.6) | 12 (70.6) | |
| Eastern Virginia Medical School | 13 (68.4) | 5 (29.4) | |
| Partner | 0.76 | ||
| Living with study partner | 12 (66.7) | 13 (76.5) | |
| No study partner | 3 (16.7) | 1 (5.9) | |
| Not living with study partner | 3 (16.7) | 3 (17.7) | |
| Contraceptive status | 0.22 | ||
| Abstinence | 3 (16.7) | 0 (0%) | |
| Condoms | 3 (16.7) | 2 (11.8) | |
| Sterilization of either partner | 15 (66.7) | 12 (88.2) | |
| Microbiota community state type | |||
| CST IVA/B at Baseline | 7 (36.8) | 11 (64.7) | 0.10 |
| CST IVA/B at Month 1 | 3 (20.0) | 14 (87.5) | <0.01 |
| CST IVA/B at Month 2 | 0 (0) | 16 (94.1) | <0.01 |
| CST IVA/B at Month 3 | 3 (23.1) | 16 (94.1) | <0.01 |
| Continuous demographic variables | |||
| Age (mean, standard deviation) | 39.4 (5.9) | 36.7 (6.2) | 0.12 |
| BMI (mean, standard deviation) | 26.2 (2.3) | 25.9 (3.4) | 0.78 |