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. 2022 Mar 8;10:794037. doi: 10.3389/fbioe.2022.794037

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Copyright © 2022 Luo, Liang, Wan, Liu, Fu, Mo, Meng and Mo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HA promotes MSCs-ECFCs proliferation and migration through miR-139-5p. (A,C). Wound healing assays were performed to assess the migration of MSCs-ECFCs transfected with miR-139-5p mimics and HA-MSCs-ECFCs transfected with miR-139-5p inhibitors, respectively. (B). CCK8 assays were performed to assess the proliferation. (D). Flow cytometry of CD31 sorted from HA-MSC-ECFC transfected with NC mimics (red) or miR-139-5p mimics (grey). (E). Quantification of flow cytometry. (n = 3 independent experiments, Error bars: mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001).