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. 2022 Mar 8;13:849403. doi: 10.3389/fphys.2022.849403

Table 3.

LncRNAs in PC-AKI, post-transplant AKI, and cisplatin induced AKI.

AKI LncRNA Expression Regulation network Function Reference
PC-AKI LNC_000343 down rno-miR-1956-5p/KCP Reduce interstitial fibrosis and renal injury Cheng et al. (2019)
NONRATT025462.2 down rno-miR-126a-5p, miR-200a-5p, miR-200a-5p/Cndp1 Associated with the process of antioxidation Bao et al. (2021)
NONRATT020679.2 down rno-miR-126a-5p, miR-200a-5p/Tmem184b - Bao et al. (2021)
Post-transplant AKI ATB up miR-200c /TGF-β Activate cell proliferation and cyclosporine A-mediated apoptosis Qiu et al. (2017)
XIST - miR-212-3p/ ASF1A, BRWD1 Regulate inflammatory and apoptosis Cheng and Wang (2020)
miR-122-5p/ PFKFB2 Influence thyroid hormone and AMPK signaling Cheng and Wang (2020)
Cisplatin induced AKI LncRNA 9,884 up NF-κB/macrophage migration inhibitory factor Aggravate tubular epithelial cells injury Zhang et al. (2020a)
MEG3 up AKT/TSC/mTOR Promote cisplatin-induced nephrotoxicity Jing et al. (2021)
GAS5 up miR-205-5p Aggravate renal epithelial cell apoptosis Zhang et al. (2021)
OIP5-AS1 down miR-144-5p/PKM2 Reduce the apoptosis of renal epithelial cells Chang et al. (2021a)
XLOC_032768 down TNF-α Reduce cell apoptosis Zhou et al. (2020)
PRNCR1 down miR-182-5p/EZH1 Reduce cell apoptosis Li et al. (2021a)