Table 3.
AKI | LncRNA | Expression | Regulation network | Function | Reference |
---|---|---|---|---|---|
PC-AKI | LNC_000343 | down | rno-miR-1956-5p/KCP | Reduce interstitial fibrosis and renal injury | Cheng et al. (2019) |
NONRATT025462.2 | down | rno-miR-126a-5p, miR-200a-5p, miR-200a-5p/Cndp1 | Associated with the process of antioxidation | Bao et al. (2021) | |
NONRATT020679.2 | down | rno-miR-126a-5p, miR-200a-5p/Tmem184b | - | Bao et al. (2021) | |
Post-transplant AKI | ATB | up | miR-200c /TGF-β | Activate cell proliferation and cyclosporine A-mediated apoptosis | Qiu et al. (2017) |
XIST | - | miR-212-3p/ ASF1A, BRWD1 | Regulate inflammatory and apoptosis | Cheng and Wang (2020) | |
miR-122-5p/ PFKFB2 | Influence thyroid hormone and AMPK signaling | Cheng and Wang (2020) | |||
Cisplatin induced AKI | LncRNA 9,884 | up | NF-κB/macrophage migration inhibitory factor | Aggravate tubular epithelial cells injury | Zhang et al. (2020a) |
MEG3 | up | AKT/TSC/mTOR | Promote cisplatin-induced nephrotoxicity | Jing et al. (2021) | |
GAS5 | up | miR-205-5p | Aggravate renal epithelial cell apoptosis | Zhang et al. (2021) | |
OIP5-AS1 | down | miR-144-5p/PKM2 | Reduce the apoptosis of renal epithelial cells | Chang et al. (2021a) | |
XLOC_032768 | down | TNF-α | Reduce cell apoptosis | Zhou et al. (2020) | |
PRNCR1 | down | miR-182-5p/EZH1 | Reduce cell apoptosis | Li et al. (2021a) |