Table I.
Baseline characteristics of patients developing infected vs infection free patients
Variable | Infection Free (n=46) | Infection (n=15) | P value |
---|---|---|---|
ECMO Support days | 10.4 ± 12.7 | 34 ± 24.8 | <0.01 |
Age, years | 48.1 ± 15.7 | 45.5 ± 14.7 | 0.56 |
BMI, kg/m2 | 28.9 ± 9.4 | 31 ± 11.2 | 0.46 |
BSA, m2 | 1.9 ± 0.3 | 1.9 ± 0.5 | 1.00 |
Hypertension | 14 (30.4%) | 2 (13.3%) | 0.31 |
Diabetes | 7 (15.2%) | 1 (6.7%) | 0.67 |
Chronic kidney disease | 11 (23.9%) | 1 (6.7%) | 0.26 |
Smoking | 12 (26.1%) | 4 (26.7%) | 1.00 |
Inotrope | 16 (34.8%) | 4 (26.7%) | 0.75 |
Pressors | 26 (56.5%) | 8 (53.3%) | 0.13 |
Nitric oxide | 15 (32.6%) | 1 (6.7%) | 0.09 |
RESP Score | 0.8 ± 3.3 | −1.4 ± 3.1 | 0.02 |
Laboratory | |||
Hemoglobin, g/dL | 10.6 ± 2.8 | 11.3 ± 2.2 | 0.32 |
WBC, 1,000/mm3 | 13.6 ± 6.4 | 16.6 ± 12.5 | 0.38 |
Platelets, 1,000/mm3 | 231.4 ± 128 | 161.3 ± 94.2 | 0.03 |
Sodium, mEq/L | 137.1 ± 8.5 | 138.4 ± 5.5 | 0.50 |
Creatinine, mg/dL | 1.5 ± 2.4 | 1.9 ± 2.6 | 0.60 |
BUN, mg/dL | 28.3 ± 19.2 | 32.3 ± 21.9 | 0.53 |
AST, U/L | 71.1 ± 145.3 | 75.4 ± 107.7 | 0.90 |
ALT, U/L | 57.3 ± 124.1 | 59 ± 86 | 0.95 |
Total bilirubin, mg/dL | 2.1 ± 6.6 | 1 ± 0.8 | 0.27 |
Albumin, g/dL | 2.9 ± 0.8 | 2.9 ± 0.4 | 1.00 |
INR | 1.4 ± 0.7 | 1.4 ± 0.3 | 1.00 |
ABG (at cannulation) | |||
pH | 7.3 ± 0.1 | 7.3 ± 0.1 | 1.00 |
PaCO2 | 55.8 ± 21.9 | 57.5 ± 14.2 | 0.73 |
PaO2 | 116 ± 89.5 | 71.4 ± 25.1 | <0.01 |
HCO3 | 26.5 ± 6.9 | 26.5 ± 6.5 | 1.00 |
Lactate | 3.4 ± 3.4 | 4 ± 3.4 | 0.56 |
Continuous data are shown as means ± standard deviation (SD). Categorical variables are presented as number and percentage. BMI, body mass index; BSA, body surface area; RESP, Respiratory ECMO Survival Prediction; WBC, white blood cell; BUN, blood urea nitrogen; AST, aspartate aminotransferase; ALT, alanine aminotransferase; INR, international normalized ratio; PT, prothrombin time; PTT partial thromboplastin time