Table 2.

Studies on comorbidity between AN and depression clinical features

Study	Sample	Diagnostic criteria/evaluation	Results of eating behaviour disorder
Abbate-Daga et al., 20151 [7]	Revision of 62 articles	Wisconsin Card Sorting Test, the Trail Making Task parts A and B, the Brixton Test, the Rey-Osterrieth Complex Figure Test and/or Iowa Gambling Task	Significant relationship between the degree of depression and the degree of cognitive impairment in patients with AN
Torres et al., 2015 [13]	160 subjects (80 with AN and 80 C)	TAS-20/SDS	The greater the severity of depression is associated with a greater degree of alexithymia in AN
Brand-Gothelf et al., 2014 [9]	88 patients with AN	EDI-2	The greater the severity of the eating behaviour, the greater the risk of suicide attempt and the greater the number of hospitalizations
Lulé et al., 2014 [15]	30 women (15 with AN and 15 C)	WISC/EDQ/EDI-2/YSR/ CBCL/BDI-II/STAI/TAS-20/SPF	Higher degree of alexithymia in AN than in control group
Wildes et al., 2007 [11]	50 patients with AN	Mood Spectrum Self-Report	The greater the severity of depressive symptoms is associated with a higher risk of suicide attempt
Konstantynowicz et al., 2005 [12]	45 patients with AN (14 with depressive symptomatology)	HRSD/MADRS	Comorbidity entails a higher risk of osteoporosis
Wilksch and Wade., 2004 [16]	60 women (19 with AN, 20 RE and 21 C)	CES-D/EDE-Q/SSPA	Subjects with AN have greater concern for body silhouette and lower self-esteem than RE in the presence of depressive symptoms
Bizeul et al., 2003 [10]	193 patients with AN (55 with severe depression, 77 with moderate depression and 32 with mild depression)	EDI/BDI	The greater the severity of depressive symptoms the greater the severity of eating behaviours
Sexton et al., 1998 [14]	53 with ED and 14 C	TAS/BDI/SCID	Alexithymia scores higher in RAN. Alexithymia presents a strong association with the severity of the depression and avoidant personality

AN, anorexia nervosa; BDI, Beck Depression Inventory; BN, bulimia nervosa; C, controls; CBCL, Child Behaviour Checklist; CES-D, Center for Epidemiological Studies Depression Scale; ED, eating disorder; EDI, Eating Disorder Inventory; EDQ, Eating Disorder Questionnaire; EDE-Q, Eating Disorder Examination Questionnaire; HRSD, Hamilton Rating Scales for Depression; MADRS, Montgomery-Asberg Depression Rating Scale; SCID, Structured Clinical Interviews for DSM-III-R; SDS, Zung-Self Rating Depression Scale; SSPA, Self-Perception Profile for Adolescents; STAI, State-Trait Anxiety Inventory; SPF, Saarbrücker Personlichkeitsfragebogen; RE, restrictive eaters; TAS, Toronto Alexithymia Scale; YSR: Youth Self Report; WISC, Wechsler Intelligence Scale for Children