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Novel Therapeutic Strategies to Reduce Visceral Adipose Tissue for Use in NAFLD
| Novel Therapeutic Target | Mechanism of action |
|---|---|
| Adiponectin replacement | Increase fatty acid oxidation, reduce oxidative stress and liver fibrosis |
| Leptin replacement | Promote lipid mobilization, reduce liver fat deposition |
| TZDs (PPAR‐γ agonist) | Increase circulating adiponectin levels, regulate inflammation, improve fibrosis |
| SGLT‐2 inhibitor | Reduce ectopic fat, reverse hepatic fibrosis |
